Structure of PDB 6hsn Chain A

Receptor sequence
>6hsnA (length=411) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPF
PASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIP
CGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGE
CVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLL
PGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVI
ITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVR
KIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLD
PRPEYHRCILTWHHQEPLPWAQSTLMSMRSANGLLMLPPKTEQYVELHKG
EVVDVMVIGRL
3D structure
PDB6hsn Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.10.1.1: molybdopterin molybdotransferase.
2.7.7.75: molybdopterin adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M326 D327 F330 R653 Y673 M711 P713 V727 D729 M8 D9 F12 R335 Y355 M386 P388 V402 D404
BS02 ADP A S505 E509 L510 D524 S525 N526 G572 G573 V574 S575 D580 G626 N627 P628 S187 E191 L192 D206 S207 N208 G254 G255 V256 S257 D262 G308 N309 P310
Gene Ontology
Biological Process
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0032324 molybdopterin cofactor biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:6hsn, PDBe:6hsn, PDBj:6hsn
PDBsum6hsn
PubMed30704910
UniProtQ03555|GEPH_RAT Gephyrin (Gene Name=Gphn)

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