Structure of PDB 6hpr Chain A

Receptor sequence
>6hprA (length=63) Species: 9606 (Homo sapiens) [Search protein sequence]
LSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPIC
RGIIKGTVRTFLS
3D structure
PDB6hpr Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C571 C574 C595 C16 C19 C40
BS02 ZN A C586 H588 C602 C605 C31 H33 C47 C50
External links
PDB RCSB:6hpr, PDBe:6hpr, PDBj:6hpr
PDBsum6hpr
PubMed30523153
UniProtQ13490|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (Gene Name=BIRC2)

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