Structure of PDB 6hov Chain A

Receptor sequence
>6hovA (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTE
3D structure
PDB6hov Biochemical and cellular mechanism of protein kinase CK2 inhibition by deceptive curcumin.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FER A W81 P82 V87 L92 N140 I146 W40 P41 V46 L51 N99 I105 PDBbind-CN: -logKd/Ki=3.30,Kd>500uM
External links
PDB RCSB:6hov, PDBe:6hov, PDBj:6hov
PDBsum6hov
PubMed31661600
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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