Structure of PDB 6ho1 Chain A

Receptor sequence
>6ho1A (length=187) Species: 83331 (Mycobacterium tuberculosis CDC1551) [Search protein sequence]
RELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLT
LLDRVVNQADMALQTLAENTDRENMWRTGINVFFETFGSHKAVTRAGQAA
RATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNL
MNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGE
3D structure
PDB6ho1 A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GFW A M102 W103 G106 I107 F110 M142 W145 Y148 T149 N176 N179 W207 M75 W76 G79 I80 F83 M115 W118 Y121 T122 N149 N152 W180
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0046677 response to antibiotic
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:6ho1, PDBe:6ho1, PDBj:6ho1
PDBsum6ho1
PubMed30553830
UniProtP9WMC1|ETHR_MYCTU HTH-type transcriptional regulator EthR (Gene Name=ethR)

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