Structure of PDB 6hmf Chain A

Receptor sequence
>6hmfA (length=440) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence]
VVLDKYGYPILYYSKYEDVVIEWNPSVTPVQIEKNYEVKFDVRQVVEAYA
SLFKSRLSKLKRILRENPEISNVVDIGKLNYVSGDEEVTIIGLVNSKRET
NRGLIFEVEDKTGIVKVFLPKDSEDYREAFKVLPDAVVAFKGFYSKKGIF
FANKFYLPDVPLYRKQKPPLEEKVYAILISDIHVGSREFCEKAFLKFLEW
LNGHVESKEEEEIVSRVKYLIIAGDVVDGIGIYPGQYSDLVIPDIFDQYE
ALANLLANVPEHITMFIGPGNADAARPAIPQPEFYKEYAKPIYKLKNAII
ISNPAVIRLHGRDFLIAHGRGIEDVVSFVPGLTHHKPGLPMVELLKMRHL
APTFGGKVPIAPDPEDLLVIEEVPDLVQMGHVHVYDAVVYRGVQLVNSAT
WQAQTEFQKMVNIVPTPAKVPVVDVESARVVKVLDFSGWC
3D structure
PDB6hmf Structure of the DP1-DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.1: exodeoxyribonuclease I.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A D360 H362 D404 H562 D181 H183 D225 H383
BS02 ZN A D404 N450 H497 H560 D225 N271 H318 H381
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:6hmf, PDBe:6hmf, PDBj:6hmf
PDBsum6hmf
PubMed30657780
UniProtQ9V2F3|DP2S_PYRAB DNA polymerase II small subunit (Gene Name=polB)

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