Structure of PDB 6hm4 Chain A

Receptor sequence
>6hm4A (length=182) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
KPLKGFVICCTSIDLKQRTEISTKATKLGAAYRSDFTKDVTHLIAGDFDT
PKYKFAAKSRPDIKIMSSEWIPVLYESWVQGEDLDDGLLVDKHFLPTLFK
CRVCLTNIGQPERSRIENYVLKHGGTFCPDLTRDVTHLIAGTSSGRKYEY
ALKWKINVVCVEWLWQSIQRNAVLEPQYFQLD
3D structure
PDB6hm4 BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands.
ChainA
Resolution1.77019 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A T110 R117 P133 D134 L135 R137 R150 K151 Y154 T106 R113 P129 D130 L131 R133 R146 K147 Y150
External links
PDB RCSB:6hm4, PDBe:6hm4, PDBj:6hm4
PDBsum6hm4
PubMed30295604
UniProtP32372|RAD4_SCHPO S-M checkpoint control protein rad4 (Gene Name=rad4)

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