Structure of PDB 6hlx Chain A

Receptor sequence

>6hlxA (length=491) Species: 358 (Agrobacterium tumefaciens)

GTLYFGLSGEPSTLDTVVQPGTSGRTVKLAIHRGLVNYGIDGKISPELAE
SYEVSPDAKEFTFHLRQAKFHDGTTVTSADVKASLERILDPKGKASFRNE
LSSISKIETPDEKTVKLTLSTPSVAMIDYLALPESVIVPAAWLAKNADNP
NAAPVGAGPFKFAGWTRGREITVKKFDDYYKKGKPDLDEVHYVFYSDENT
RVNALKSGDVDIIDYVPAKDAADIAKGPETQLLRNTGPFMGLQFNTKFEP
FSKPEVRQAIAYAVDRSAIINTAFNGLGSPIFGIAIPKGYMGYSDAKANY
FSHHVEKAKALLAKAGYPNGFEVRLLATSQYSFQQNTAIAIQSELAKIGI
KVKLDLPDWASRMAKASTGDYDFTVMGSLGEITDADWLSNYYYGGDKLVR
TNNSPYFNDQQINDLLDKGRATVDKAERVKIYDAFVDRALELSPLVYFMW
REQNYAVKKGVTGFTNMPGFLTFQSGLSIENTKIEHHHHHH

3D structure

• PDB: 6hlx Structural basis for two efficient modes of agropinic acid opine import into the bacterial pathogenAgrobacterium tumefaciens.
• Chain: A
• Resolution: 1.65 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	G9Z	A	G45 Y239 Q267 Y355 F357 Q358 W383 R386 G401 T425 N426 R475	G21 Y215 Q243 Y331 F333 Q334 W359 R362 G377 T401 N402 R451	PDBbind-CN: -logKd/Ki=7.17,Kd=67nM
BS02	ZN	A	E194 H215	E170 H191
BS03	ZN	A	D235 H511 H513	D211 H487 H489
BS04	ZN	A	E77 H88	E53 H64

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding
• GO:1904680 peptide transmembrane transporter activity

Biological Process

• GO:0015833 peptide transport
• GO:0055085 transmembrane transport

Cellular Component

• GO:0030288 outer membrane-bounded periplasmic space
• GO:0042597 periplasmic space
• GO:0043190 ATP-binding cassette (ABC) transporter complex

External links

• PDB: RCSB:6hlx, PDBe:6hlx, PDBj:6hlx
• PDBsum: 6hlx
• PubMed: 30552142
• UniProt: O50260