Structure of PDB 6hl0 Chain A

Receptor sequence
>6hl0A (length=231) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEM
ATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKL
PSGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVI
LSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTEL
RTFNHHHAEMLMSWRVNDHKFTPLLCEIWDV
3D structure
PDB6hl0 Molecular tuning of farnesoid X receptor partial agonism.
ChainA
Resolution1.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K303 H313 Q316 I317 K321 P463 L464 E467 K63 H73 Q76 I77 K81 P223 L224 E227
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0032052 bile acid binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0038183 bile acid signaling pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:6hl0, PDBe:6hl0, PDBj:6hl0
PDBsum6hl0
PubMed31266946
UniProtQ96RI1|NR1H4_HUMAN Bile acid receptor (Gene Name=NR1H4)

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