Structure of PDB 6hi8 Chain A

Receptor sequence
>6hi8A (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQP
MDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRA
CALRDTAYAIIKEELDEDFEQLCEEIQESR
3D structure
PDB6hi8 Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G6W A V1008 V1013 Y1063 N1064 V30 V35 Y85 N86 BindingDB: IC50=>150000nM
External links
PDB RCSB:6hi8, PDBe:6hi8, PDBj:6hi8
PDBsum6hi8
PubMed32832026
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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