Structure of PDB 6h7d Chain A

Receptor sequence
>6h7dA (length=487) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
VTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKA
KHDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGL
AFLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRG
ALNIGFQMAITIGILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGS
FILPDTPNSMLERGKNEEAKQMLKKIRGADNVDHEFQDLIDAVEAAKKVE
NPWKNIMESKYRPALIFCSAIPFFQQITGINVIMFYAPVLFKTLGFGDDA
ALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQLLVGSFI
GARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLE
IRPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFI
YFLLPETKGVPIEEMGRVWKQHWFWKKYIPEDAIIGG
3D structure
PDB6h7d Crystal structure of the plant symporter STP10 illuminates sugar uptake mechanism in monosaccharide transporter superfamily.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A Q177 I184 Q295 N301 N332 G406 W410 Q157 I164 Q275 N281 N312 G386 W390 MOAD: Kd=3.2uM
PDBbind-CN: -logKd/Ki=5.49,Ki=3.2uM
Gene Ontology
Molecular Function
GO:0005354 galactose transmembrane transporter activity
GO:0009679 hexose:proton symporter activity
GO:0015144 carbohydrate transmembrane transporter activity
GO:0015145 monosaccharide transmembrane transporter activity
GO:0015293 symporter activity
GO:0015578 mannose transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0008645 hexose transmembrane transport
GO:0015749 monosaccharide transmembrane transport
GO:0015757 galactose transmembrane transport
GO:0015761 mannose transmembrane transport
GO:0055085 transmembrane transport
GO:0071333 cellular response to glucose stimulus
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:6h7d, PDBe:6h7d, PDBj:6h7d
PDBsum6h7d
PubMed30679446
UniProtQ9LT15|STP10_ARATH Sugar transport protein 10 (Gene Name=STP10)

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