Structure of PDB 6h6h Chain A

Receptor sequence
>6h6hA (length=272) Species: 10090 (Mus musculus) [Search protein sequence]
GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAP
WMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSG
CDLGSDWRLLRGYQQYAYDGRDYIALNEDLKTWTAADMAAQITRRKWEQS
GAAEHYKAYLEGECVEWLHRYLKNGNRTDSPKAHVTHHPRSKGEVTLRCW
ALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKE
QNYTCRVYHEGLPEPLTLRWEP
3D structure
PDB6h6h Crystal structures of H-2Db and H-2Dbm13 with cancer-associated Ad 10 peptide reveal that subtle changes in the peptide environment impact thermostability and alloreactivity
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 Q97 Y123 T143 K146 W147 S150 H155 Y156 Y159 E163 W167 Y171 Y7 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 Q97 Y123 T143 K146 W147 S150 H155 Y156 Y159 E163 W167 Y171
Gene Ontology
Biological Process
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0042612 MHC class I protein complex
GO:0098553 lumenal side of endoplasmic reticulum membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:6h6h, PDBe:6h6h, PDBj:6h6h
PDBsum6h6h
PubMed
UniProtQ31167

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