Structure of PDB 6h4g Chain A

Receptor sequence
>6h4gA (length=274) Species: 185431 (Trypanosoma brucei brucei TREU927) [Search protein sequence]
AKSYVAPYFEKSEDETALILKLLTYNVLFSFLDSRDLMTVAGAMWRVEFK
QDDCIMEAGQTTCDKLYIIQDGKADIIKEGQKVYLKVEGTAVGELALMYQ
TPRAATVKVCTPELIAWALDRDTYRHLVMGSAIRRRETYIQFLTNIPFLS
GLDNYEKLQLADALSSDEFEPGDYIIRYGEEGEWLYIILEGSVDVVGRDD
DGNEKHVWEFGKGDHVGELEFLNNHANVADVVAKTHVVTAKLNRRHFEMC
LGPVIDVLKRTSQQPNYEYYQSKL
3D structure
PDB6h4g Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei: E311A, T318R, V319A mutant
ChainA
Resolution2.14352 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A M271 I291 Y299 V307 G308 E309 L310 A311 R318 A319 A320 V322 Y370 M56 I76 Y84 V92 G93 E94 L95 A96 R103 A104 A105 V107 Y155
BS02 NOS A V410 V422 V431 G432 L434 E435 A444 N481 Y482 Y484 Y485 V195 V207 V216 G217 L219 E220 A229 N266 Y267 Y269 Y270
Gene Ontology
Molecular Function
GO:0008603 cAMP-dependent protein kinase regulator activity
Biological Process
GO:0001932 regulation of protein phosphorylation
Cellular Component
GO:0005952 cAMP-dependent protein kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6h4g, PDBe:6h4g, PDBj:6h4g
PDBsum6h4g
PubMed38517938
UniProtQ385V6

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