Structure of PDB 6h41 Chain A

Receptor sequence
>6h41A (length=309) Species: 9606 (Homo sapiens) [Search protein sequence]
KISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRNVNLEYQVKINAPKEDD
YETRITESKAVTILHKGFSASVRTILQNDHSLLASSWASAELHAPPGSPG
TSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYG
SWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRP
FDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKI
HNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWS
QPIYVGFSR
3D structure
PDB6h41 Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121.
ChainA
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q25 K53 D55 Y57 K65 A66 V67 Y155 L184 R188 D189 W190 Q19 K47 D49 Y51 K59 A60 V61 Y149 L178 R182 D183 W184
Gene Ontology
Molecular Function
GO:0004896 cytokine receptor activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:6h41, PDBe:6h41, PDBj:6h41
PDBsum6h41
PubMed30529748
UniProtQ01344|IL5RA_HUMAN Interleukin-5 receptor subunit alpha (Gene Name=IL5RA)

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