Structure of PDB 6h11 Chain A

Receptor sequence
>6h11A (length=329) Species: 9606 (Homo sapiens) [Search protein sequence]
AQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKAR
ETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKY
QTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTI
QDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPK
TWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIP
FNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQC
SCGEARVTFSMDAFVRILQPERYDLWKRG
3D structure
PDB6h11 Crystal Structure of KDM4D with tetrazolylhydrazide ligand AA028
ChainA
Resolution1.516 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.14.11.66: [histone H3]-trimethyl-L-lysine(9) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C238 H244 C310 C312 C228 H234 C300 C302
BS02 FHT A H90 Y136 D139 Y181 F189 H192 E194 N202 K210 K245 H280 H80 Y126 D129 Y171 F179 H182 E184 N192 K200 K235 H270
External links
PDB RCSB:6h11, PDBe:6h11, PDBj:6h11
PDBsum6h11
PubMed
UniProtQ6B0I6|KDM4D_HUMAN Lysine-specific demethylase 4D (Gene Name=KDM4D)

[Back to BioLiP]