Structure of PDB 6gx6 Chain A

Receptor sequence
>6gx6A (length=159) Species: 9606 (Homo sapiens) [Search protein sequence]
GSMNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDES
WALKAIEALSGKIELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLD
SLLVQYGVVESCEQVNTDSETAVVNVTYSSKDQARQALDKLNGFQLENFT
LKVAYIPDE
3D structure
PDB6gx6 Structural basis of IMP3 RRM12 recognition of RNA.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Y5 K36 Y39 F41 S73 V74 R79 Y7 K38 Y41 F43 S75 V76 R81 PDBbind-CN: Kd=4.7uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6gx6, PDBe:6gx6, PDBj:6gx6
PDBsum6gx6
PubMed30135093
UniProtO00425|IF2B3_HUMAN Insulin-like growth factor 2 mRNA-binding protein 3 (Gene Name=IGF2BP3)

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