Structure of PDB 6gwi Chain A

Receptor sequence
>6gwiA (length=449) Species: 768066 (Halomonas elongata DSM 2581) [Search protein sequence]
QTQDYQALDRAHHLHPFTDFKALGEEGSRVVTHAEGVYIHDSEGNRILDG
MAGLWCVNLGYGRRELVEAATAQLEQLPYYNTFFKTTHPPAVRLAEKLCD
LAPAHINRVFFTGSGSEANDTVLRMVRRYWALKGQPDKQWIIGRENAYHG
STLAGMSLGGMAPMHAQGGPCVPGIAHIRQPYWFGEGRDMSPEAFGQTCA
EALEEKILELGEEKVAAFIAEPVQGAGGAIMPPESYWPAVKKVLAKYDIL
LVADEVICGFGRLGEWFGSQHYGLEPDLMPIAKGLSSGYLPIGGVLVGDR
VAETLIEEGGEFFHGFTYSGHPTCAAVALKNLELLEAEGVVDRVRDDLGP
YLAERWASLVDHPIVGEARSLGLMGALELVADKTTGQRFDKSLGAGNLCR
DLCFANGLVMRSVGDTMIISPPLVIRREEIDELVELARRALDETARQLT
3D structure
PDB6gwi Widely applicable background depletion step enables transaminase evolution through solid-phase screening.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F18 Y149 D255 K284
Catalytic site (residue number reindexed from 1) F17 Y148 D254 K283
Enzyme Commision number 2.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A S115 G116 S117 Y149 H150 G151 E222 D255 V257 I258 K284 S114 G115 S116 Y148 H149 G150 E221 D254 V256 I257 K283
BS02 PLP A F317 T318 F316 T317
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding

View graph for
Molecular Function
External links
PDB RCSB:6gwi, PDBe:6gwi, PDBj:6gwi
PDBsum6gwi
PubMed31360401
UniProtE1V913

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