Structure of PDB 6gwc Chain A

Receptor sequence

>6gwcA (length=431) Species: 9940 (Ovis aries)

MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSGDDSFNTFFSET
GAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARG
HYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMER
LSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDN
EAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQ
TNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCD
PRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGIN
YQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVH
WYVGEGMEEGEFSEAREDMAALEKDYEEVGV

3D structure

• PDB: 6gwc Selection and Characterization of Artificial Proteins Targeting the Tubulin alpha Subunit.
• Chain: A
• Resolution: 2.6 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GTP	A	Q11 A12 Q15 A99 N101 S140 G143 G144 T145 G146 T179 E183 N206 Y224 N228	Q11 A12 Q15 A93 N95 S134 G137 G138 T139 G140 T173 E177 N200 Y218 N222

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sat Feb 22 17:05:14 2025

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '6gwc', asym_id = 'A', title = 'Selection and Characterization of Artificial Proteins Targeting the Tubulin alpha Subunit.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='6gwc', asym_id='A', title='Selection and Characterization of Artificial Proteins Targeting the Tubulin alpha Subunit.')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0005200,0005525,0005874,0007017', uniprot = '', pdbid = '6gwc', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0005200,0005525,0005874,0007017', uniprot='', pdbid='6gwc', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>