Structure of PDB 6gw3 Chain A

Receptor sequence
>6gw3A (length=383) Species: 3483 (Cannabis sativa) [Search protein sequence]
HLRAEGPASVLAIGTANPENILLQDEFPDYYFRVTKSEHMTQLKEKFRKI
CDKSMIRKRNCFLNEEHLKQNPRLVEHEMQTLDARQDMLVVEVPKLGKDA
CAKAIKEWGQPKSKITHLIFTSASTTDMPGADYHCAKLLGLSPSVKRVMM
YQLGCYGGGTVLRIAKDIAENNKGARVLAVCCDIMACLFRGPSESDLELL
VGQAIFGDGAAAVIVGAEPDESVGERPIFELVSTGQTILPNSEGTIGGHI
REAGLIFDLHKDVPMLISNNIEKCLIEAFTPIGISDWNSIFWITHPGGKA
ILDKVEEKLHLKSDKFVDSRHVLSEHGNMSSSTVLFVMDELRKRSLEEGK
STTGDGFEWGVLFGFGPGLTVERVVVRSVPIKY
3D structure
PDB6gw3 Structure of a PKS class III from Cannabis sativa
ChainA
Resolution1.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.206: 3,5,7-trioxododecanoyl-CoA synthase.
4.4.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 COA A K55 A157 E200 V203 L261 K263 G299 G300 K301 A302 K53 A155 E198 V201 L259 K261 G297 G298 K299 A300
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0016829 lyase activity
Biological Process
GO:0009058 biosynthetic process
GO:0016114 terpenoid biosynthetic process
GO:0030639 polyketide biosynthetic process
GO:1901696 cannabinoid biosynthetic process

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:6gw3, PDBe:6gw3, PDBj:6gw3
PDBsum6gw3
PubMed
UniProtB1Q2B6|OLIS_CANSA 3,5,7-trioxododecanoyl-CoA synthase (Gene Name=OLS)

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