Structure of PDB 6gvl Chain A

Receptor sequence

>6gvlA (length=199) Species: 9606 (Homo sapiens) [Search protein sequence]

VPDTPTRLVFSALGPTSLRVSWQEPRCPLQGYSVEYQLLNGGELHRLNIP
NPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQLPGSAFT
LSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPA
TAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIES

3D structure

PDB

6gvl Integrin alpha 6 beta 4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes.

Chain

Resolution

2.05 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	R1463 L1464 V1465 F1466 S1467 R1542 G1544 P1562 G1563 L1568 L1577 V1578 F1579 T1580 A1581 P1656 E1657 R1658 E1659 I1661 I1662 T1663 I1664 E1665	R7 L8 V9 F10 S11 R84 G86 P95 G96 L101 L110 V111 F112 T113 A114 P189 E190 R191 E192 I194 I195 T196 I197 E198

External links

PDB	RCSB:6gvl, PDBe:6gvl, PDBj:6gvl
PDBsum	6gvl
PubMed	31006587
UniProt	P16144\|ITB4_HUMAN Integrin beta-4 (Gene Name=ITGB4)

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