Structure of PDB 6grb Chain A

Receptor sequence
>6grbA (length=398) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]
GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARG
GSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNKSTAMAKRLIRLFGFTAHD
APGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGGPPTHV
TLHDAKKIAEGPSGLDREGMVLVALMSGGDYLPDGIPGCGIKVACQAAKA
GFGKELCRIKRAITEWKQRLLHELRTNESGFFRTKHKALEIPENFPNMEV
LRYYTHPVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDWTFRPGAI
KLIKVLAPGLLVQRCLDRKEESTLVKGISMRREHFSTDATPELRVSFIPA
ELVGLDPGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVEDWEEGQRS
3D structure
PDB6grb A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y7 E140 D141 T257 K258 H259 Y6 E124 D125 T234 K235 H236
BS02 dna A F44 G207 G209 I210 K211 R256 F43 G188 G190 I191 K192 R233
BS03 MG A D141 D143 D125 D127
BS04 MG A E122 D143 E106 D127
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0008821 crossover junction DNA endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:6grb, PDBe:6grb, PDBj:6grb
PDBsum6grb
PubMed30247722
UniProtG0RYN2

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