Structure of PDB 6gpg Chain A

Receptor sequence
>6gpgA (length=651) Species: 9606 (Homo sapiens) [Search protein sequence]
SPFKPRNYQLELALPAMKGKNTIICAPTGFGKTFVSLLICEHHLKKFPQG
QKGKVVFFANQIPVYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIV
ENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMF
NYLDQKLGGSSGPLPQVIGLTASVGVGDAKNTDEALDYICKLCASLDASV
IATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMRDTESLAKR
ICKDLNREFGTQKYEQWIVTVQKACMVFQMPDKDEESRICKALFLYTSHL
RKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQ
ELESVSRDPSNENPKLEDLCFILQEEYHLNPETITILFVKTRALVDALKN
WIEGNPKLSFLKPGILTGDHNILIATSVADEGIDIAQCNLVILYEYVGNV
IKMIQTRGRGRARGSKCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQTW
DEAVFREKILHIQTHEKFIRDSQEKPKPVPDKENKKLLCRKCKALACYTA
DVRVIEECHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSH
DWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPA
E
3D structure
PDB6gpg Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants.
ChainA
Resolution2.894 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6gpg, PDBe:6gpg, PDBj:6gpg
PDBsum6gpg
PubMed30047865
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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