Structure of PDB 6gon Chain A

Receptor sequence
>6gonA (length=114) Species: 8175 (Sparus aurata) [Search protein sequence]
CPLMVKILDAVKGTPAGSVALKVSQKTADGGWTQIATGVTDATGEIHNLI
TEQQFPAGVYRVEFDTKAYWTNQGSTPFHEVAEVVFDAHPEGHRHYTLAL
LLSPFSYTTTAVVS
3D structure
PDB6gon Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 8PF A K15 A108 L110 K6 A99 L101 MOAD: Kd=2.16uM
PDBbind-CN: -logKd/Ki=5.67,Kd=2.16uM
Gene Ontology
Molecular Function
GO:0005179 hormone activity
GO:0070324 thyroid hormone binding
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0007165 signal transduction
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6gon, PDBe:6gon, PDBj:6gon
PDBsum6gon
PubMed30226982
UniProtQ9PTT3

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