Structure of PDB 6gkk Chain A

Receptor sequence
>6gkkA (length=182) Species: 10090 (Mus musculus) [Search protein sequence]
NPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHI
QLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRF
WLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHI
GRVYKERLGLPPKIVIGYQSHADTATKNRFVV
3D structure
PDB6gkk Translation initiation factor 4E in complex with beta-phosphorothioate trinucleotide mRNA 5' cap diastereomer 1 (m7GppSpApG D1)
ChainA
Resolution1.858 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 WZO A W56 M101 W102 E103 R157 K162 W27 M72 W73 E74 R128 K133
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6gkk, PDBe:6gkk, PDBj:6gkk
PDBsum6gkk
PubMed
UniProtP63073|IF4E_MOUSE Eukaryotic translation initiation factor 4E (Gene Name=Eif4e)

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