Structure of PDB 6ghn Chain A

Receptor sequence

>6ghnA (length=269) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDQDTELVETRPAGDGTFQKWAAVVVPSGEEQ
RYTCHVQHEGLPEPVTLRW

3D structure

PDB

6ghn Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.

Chain

Resolution

2.542 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Y7 M45 E63 S66 I73 N77 L81 Y84 W97 H99 F116 S143 K146 E152 Y159 W167 Y171	Y7 M45 E63 S66 I73 N77 L81 Y84 W97 H99 F116 S143 K146 E152 Y159 W167 Y171

External links

PDB	RCSB:6ghn, PDBe:6ghn, PDBj:6ghn
PDBsum	6ghn
PubMed	30087334
UniProt	P13747\|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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