Structure of PDB 6ggm Chain A

Receptor sequence
>6ggmA (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRW
3D structure
PDB6ggm Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
ChainA
Resolution2.734 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 H9 R62 E63 S66 A67 T70 I73 N77 Y84 W97 H99 F116 S143 Q156 Y159 W167 Y171 Y7 H9 R62 E63 S66 A67 T70 I73 N77 Y84 W97 H99 F116 S143 Q156 Y159 W167 Y171
BS02 ZN A H181 E183 H181 E183
BS03 ZN A E152 H155 E152 H155
BS04 ZN A D196 H197 D196 H197
External links
PDB RCSB:6ggm, PDBe:6ggm, PDBj:6ggm
PDBsum6ggm
PubMed30087334
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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