Structure of PDB 6ggi Chain A

Receptor sequence
>6ggiA (length=294) Species: 67327 (Streptomyces melanosporofaciens) [Search protein sequence]
GRSSVRPYLEECTRRFQEMFDRHVVTRPTKVELTDAELREVIDDCNAAVA
PLGKTVSDERWISYVGVVLWSQSPRHIKDMEAFKAVCVLNCVTFVWDDMD
PALHDFGLFLPQLRKICEKYYGPEDAEVAYEAARAFVTSDHMFRDSPIKA
ALCTTSPEQYFRFRVTDIGVDFWMKMSYPIYRHPEFTEHAKTSLAARMTT
RGLTIVNDFYSYDREVSLGQITNCFRLCDVSDETAFKEFFQARLDDMIED
IECIKAFDQLTQDVFLDLIYGNFVWTTSNKRYKTAVNDVNSRIQ
3D structure
PDB6ggi Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis.
ChainA
Resolution1.803 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.3.146: cyclooctat-9-en-7-ol synthase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A N220 S224 E228 N207 S211 E215
BS02 MG A E131 Y134 E118 Y121
BS03 MG A E72 D301 E59 D288
BS04 EXW A N103 F107 F149 I181 G182 V183 F185 W186 L216 W288 N90 F94 F136 I168 G169 V170 F172 W173 L203 W275
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6ggi, PDBe:6ggi, PDBj:6ggi
PDBsum6ggi
PubMed30266969
UniProtC9K1X5|COTB2_STRMJ Cyclooctat-9-en-7-ol synthase (Gene Name=CotB2)

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