Structure of PDB 6gfg Chain A

Receptor sequence
>6gfgA (length=420) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
EVLFQGPMEMILEEKDASDWIYRGEGGANLVLAYAGSSPLFVGKVIRIQK
ARRNDSVLTSDEQHLWRENNELISSPNKEVLEQRYVQNVIIPLLGPKHVD
AGVRVSVSKEFLECVDKKVTKQRPLWRVNAANVDTSHDSALILNDHSLFD
CISVEIKPKCGFLPTSRFIGKENMLKTSVSRFKMHQLLKLEYIEISEESE
YDPLDLFSGSKERVLEAIKALYSTPQNNFRVFLNGSLILGGSGESTGRTS
PEIGYAFEDALKGFIQSEDGHRTECFLQLVSDAVYGSGVLDRLLEIQKLD
KLDIEGAIHCYYDIINQPCPICKEELSLHALPLDESLKIVKEYLIAATAK
DCSIMISFQSRNAWDSEPSGDYVSLKPTNQTFDYKVHFIDLSLKPLKRME
SYYKLDKKIISFYNRKQKAE
3D structure
PDB6gfg A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.158: inositol-pentakisphosphate 2-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KGN A G20 R130 K168 K170 R192 N238 D368 K411 R415 Y419 G27 R127 K157 K159 R181 N227 D351 K394 R398 Y402
BS02 ADP A E18 G19 N22 D148 H149 E166 D407 E25 G26 N29 D145 H146 E155 D390
BS03 ZN A H320 C330 C333 H346 H309 C319 C322 H329
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0032942 inositol-1,4,5,6-tetrakisphosphate 2-kinase activity
GO:0035299 inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity
GO:0046872 metal ion binding
GO:0102731 inositol-1,3,4,6-tetrakisphosphate 2-kinase activity
Biological Process
GO:0010264 myo-inositol hexakisphosphate biosynthetic process
GO:0016310 phosphorylation
GO:0030643 intracellular phosphate ion homeostasis
GO:0042742 defense response to bacterium
GO:0048527 lateral root development
GO:0050832 defense response to fungus
GO:0051607 defense response to virus
GO:0055062 phosphate ion homeostasis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gfg, PDBe:6gfg, PDBj:6gfg
PDBsum6gfg
PubMed30160967
UniProtQ93YN9|IPPK_ARATH Inositol-pentakisphosphate 2-kinase (Gene Name=IPK1)

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