Structure of PDB 6gc5 Chain A

Receptor sequence
>6gc5A (length=79) Species: 9606 (Homo sapiens) [Search protein sequence]
GWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTM
TNYEEAAMAIASLNGYRLGDKILQVSFKT
3D structure
PDB6gc5 Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A F247 Y249 Q253 I276 R277 K285 F289 Q316 K320 T321 F5 Y7 Q11 I34 R35 K43 F47 Q74 K78 T79 PDBbind-CN: Kd=0.65uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6gc5, PDBe:6gc5, PDBj:6gc5
PDBsum6gc5
PubMed30718402
UniProtQ15717|ELAV1_HUMAN ELAV-like protein 1 (Gene Name=ELAVL1)

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