Structure of PDB 6gat Chain A

Receptor sequence
>6gatA (length=66) Species: 162425 (Aspergillus nidulans) [Search protein sequence]
MKNGEQNGPTTCTNCFTQTTPVWRRNPEGQPLCNACGLFLKLHGVVRPLS
LKTDVIKKRNRNSANS
3D structure
PDB6gat The solution structure of the Leu22-->Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R24 R59 R24 R59 PDBbind-CN: Kd=20uM
BS02 dna A P21 N34 F39 R47 I56 R59 R61 P21 N34 F39 R47 I56 R59 R61 PDBbind-CN: Kd=20uM
BS03 ZN A C12 C15 C33 C36 C12 C15 C33 C36
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:6gat, PDBe:6gat, PDBj:6gat
PDBsum6gat
PubMed9533884
UniProtP17429|AREA_EMENI Nitrogen regulatory protein areA (Gene Name=areA)

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