Structure of PDB 6g9w Chain A

Receptor sequence
>6g9wA (length=460) Species: 330879 (Aspergillus fumigatus Af293) [Search protein sequence]
PSAEEFQQLRKKYTDAGQGHVFAFVDELQTGERSQLFHQLSSFDPVRINE
LADKALNPPASLEPLPDIATASILDSDPKDLEQWYEEGLKLVAGNKVAVV
LMAGGQGTRLGSSAPKGCFDIGLPSHKSLFQIQAERIAKLQLLAQRISGK
EAVIPWYVMTSGPTRKPTEEFFEQHKYFGLNKSDVIIFEQGVLPCISNEG
KILMESKFKVAVAPDGNGGIYQALLTSGVREDMRKRGIEHIHTYCVDNCL
VKVADPVFIGFAASKQVDIATKVVRKRNATESVGLILQKNGKPDVVEYSE
IDKETAEAKDPKQPDVLKFRAANIVNHYYSFKFFESIELWAHKLPHHVAR
KKICIPNGIKLEQFVFDVFPMTPLEKFACIEVRREDEFSPLKNARGTGED
DPDTSKRDIMSQGQRWIEKAGGIVITEGVGVEVSPLISYGGEGLEFLKGR
EIKAPAFIEK
3D structure
PDB6g9w A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.23: UDP-N-acetylglucosamine diphosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UTP A G136 G137 G139 T140 R141 G248 N249 E407 G104 G105 G107 T108 R109 G216 N217 E362
Gene Ontology
Molecular Function
GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity
GO:0016740 transferase activity
GO:0016779 nucleotidyltransferase activity
GO:0070569 uridylyltransferase activity
Biological Process
GO:0006048 UDP-N-acetylglucosamine biosynthetic process
GO:0043934 sporulation

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Molecular Function
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Biological Process
External links
PDB RCSB:6g9w, PDBe:6g9w, PDBj:6g9w
PDBsum6g9w
PubMed
UniProtQ4WAR0

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