Structure of PDB 6g3u Chain A

Receptor sequence
>6g3uA (length=737) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
SKITYTFTDEAPALATYSLLPIVKAFAASAGIDVETSDISLAGRILANFA
DRLEADQRIEDDLARLAVLATSPDANIIKLPNISASVPQLKGAIAELQGL
GYKVPDFPEDPQTDEEKEVRARYAKILGSAVNPVLREGNSDRRAPAAVKA
YARKHPHSMGKWSMASRSHADYMRGGDFFSSEQSITMAKAGDVRIEFVGK
DGKVEVKKQLSLQEGEVLDSMFMSCGKLRDFFEKTLQDCKETGVMWSLHV
KATMMKISHPIVFGHAVSVYYKDVFDKWGQLFEELGVNPNNGISSVYDKI
KSLPASQQEEILHDIHEVYSHRPEMAMVDSVKGITNLHIPSDVIVDASMP
AMIRNSGQMWGKDGKQKDTKAVMPESTYARIYQEMINFCKTNGAFDPTTM
GSVPNVGLMAQKAEEYGSHDKTFEMTADGTMRVVLADGSVLMQHKVETGD
IWRACQTKDAPIRDWVKLAVTRARQSDTPAIFWLDPERAHDRELRKKVEL
YLKDHDLTGLDISIMGYNEAIRVSMERLIRGKDTISVTGNVLRDYLTDLF
PIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEENYLRWDSL
GEFLALAVSLEETGIKTGNAKAKLLGKALDEATGKLLDNNKSPSRKVGDI
DNRGSHFYLAMYWAQALAAQNEDAELKAHFAPLAKALTEQEATIVAELNA
VQGKPAEIGGYYRSNPELTSKVMRPSATFNAAIDSLA
3D structure
PDB6g3u Gluconeogenic precursor availability regulates flux through the glyoxylate shunt inPseudomonas aeruginosa.
ChainA
Resolution2.707 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.42: isocitrate dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A P85 N86 S88 N136 I348 A351 T561 A563 G583 G584 S585 A586 P587 H589 R600 W601 D602 R649 P81 N82 S84 N132 I344 A347 T557 A559 G579 G580 S581 A582 P583 H585 R596 W597 D598 R645
BS02 AKG A S88 S133 R146 K255 Y420 R547 D548 S84 S129 R142 K251 Y416 R543 D544
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004450 isocitrate dehydrogenase (NADP+) activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006097 glyoxylate cycle
GO:0006099 tricarboxylic acid cycle

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6g3u, PDBe:6g3u, PDBj:6g3u
PDBsum6g3u
PubMed30030382
UniProtQ9I0L4

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