Structure of PDB 6g2y Chain A

Receptor sequence
>6g2yA (length=266) Species: 9606 (Homo sapiens) [Search protein sequence]
VVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY
GPPGCGKTLLAKAIANECQANFISIKGPELLTSEANVREIFDKARQAAPC
VLFFDELDSIAKAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAI
LRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFS
GADLTEICQRACKLAIRESIESEIRREREPVPEIRRDHFEEAMRFARRSV
SDNDIRKYEMFAQTLQ
3D structure
PDB6g2y Crystal structure of the catalytic D2 domain of the AAA+ ATPase p97 reveals a putative helical split-washer-type mechanism for substrate unfolding.
ChainA
Resolution2.153 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.6: vesicle-fusing ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A G480 G521 C522 G523 K524 T525 L526 I656 G684 A685 T688 G13 G54 C55 G56 K57 T58 L59 I173 G201 A202 T205
BS02 ELQ A R625 D627 D751 K754 Y755 R142 D144 D254 K257 Y258
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:6g2y, PDBe:6g2y, PDBj:6g2y
PDBsum6g2y
PubMed31701538
UniProtP55072|TERA_HUMAN Transitional endoplasmic reticulum ATPase (Gene Name=VCP)

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