Structure of PDB 6g2r Chain A

Receptor sequence
>6g2rA (length=158) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPE
TITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTD
KPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYA
NNDVVVPT
3D structure
PDB6g2r Improvement of Aglycone pi-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 EJK A F1 N46 Y48 I52 D54 Q133 N135 Y137 D140 F1 N46 Y48 I52 D54 Q133 N135 Y137 D140 MOAD: Kd=0.35nM
PDBbind-CN: -logKd/Ki=9.46,Kd=0.35nM
Gene Ontology
Cellular Component
GO:0009289 pilus

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6g2r, PDBe:6g2r, PDBj:6g2r
PDBsum6g2r
PubMed30710416
UniProtP08191|FIMH_ECOLI Type 1 fimbrin D-mannose specific adhesin (Gene Name=fimH)

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