Structure of PDB 6g2p Chain A

Receptor sequence

>6g2pA (length=412) Species: 243365 (Chromobacterium violaceum ATCC 12472) [Search protein sequence]

KHSSDICIVGAGISGLTCASHLLDSPACRGLSLRIFDMQQEAGGRIRSKM
LDGKASIELGAGRYSPQLHPHFQSAMQHYSQKSEVYPFTQLKFKSHVQQK
LKRAMNELSPRLKEHGKESFLQFVSRYQGHDSAVGMIRSMGYDALFLPDI
SAEMAYDIVGKHPEIQSVTDNDANQWFAAETGFAGLIQGIKAKVKAAGAR
FSLGYRLLSVRTDGDGYLLQLAGDDGWKLEHRTRHLILAIPPSAMAGLNV
DFPEAWSGARYGSLPLFKGFLTYGEPWWLDYKLDDQVLIVDNPLRKIYFK
GDKYLFFYTDSEMANYWRGCVAEGEDGYLEQIRTHLASALGIVRERIPQP
LAHVHKYWAHGVEFCRHPSALSHRDSGIIACSDAYTEHCGWMEGGLLSAR
EASRLLLQRIAA

3D structure

PDB

6g2p A semi-synthetic strategy for derivatization of the violacein natural product scaffold

Chain

Resolution

2.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.4.3.23: 7-chloro-L-tryptophan oxidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	FAD	A	G13 I14 S15 D38 M39 G45 R46 G61 A62 G63 R64 R207 L208 I241 L267 W359 G362 D389 W397 M398	G12 I13 S14 D37 M38 G44 R45 G60 A61 G62 R63 R206 L207 I240 L266 W358 G361 D383 W391 M392
BS02	TRP	A	R64 H163 Y309 V363 W397	R63 H162 Y308 V362 W391
BS03	MG	A	G11 G13 G16 A240	G10 G12 G15 A239

Gene Ontology

	Molecular Function
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

	Biological Process
GO:0017000	antibiotic biosynthetic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:6g2p, PDBe:6g2p, PDBj:6g2p
PDBsum	6g2p
PubMed
UniProt	Q9S3V1\|VIOA_CHRVO Flavin-dependent L-tryptophan oxidase VioA (Gene Name=vioA)

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