Structure of PDB 6g19 Chain A

Receptor sequence
>6g19A (length=682) Species: 10090 (Mus musculus) [Search protein sequence]
LQLRPYQMEVAQPALDGKNIIICLPTGSGKTRVAVYITKDHLDKKKQASE
SGKVIVLVNKVMLAEQLFRKEFNPYLKKWYRIIGLSGDTQLKISFPEVVK
SYDVIISTAQILENSLLNLESGDDDGVQLSDFSLIIIDECHHTNKEAVYN
NIMRRYLKQKLRNNDLKKAIPLPQILGLTASPGVGAAKKQSEAEKHILNI
CANLDAFTIKTVKENLGQLKHQIKEPCKKFVIADDTRENPFKEKLLEIMA
SIQTYCQKSPMSDFGTQHYEQWAIQMEKKAAKDGNRKDRVCAEHLRKYNE
ALQINDTIRMIDAYSHLETFYTDEKEKKFAVLNKLDETDEFLMNLFFDNK
KMLKKLAENPKYENEKLIKLRNTILEQFTRSEESSRGIIFTKTRQSTYAL
SQWIMENAKFAEVGVKAHHLIGAGHSSEVKPMTQTEQKEVISKFRTGEIN
LLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVT
SSGSGVTEREIVNDFREKMMYKAINRVQNMKPEEYAHKILELQVQSILEK
KMKVKRSIAKQYNDNPSLITLLCKNCSMLVCSGENIHVIEKMHHVNMTPE
FKGLYIVRENKALQKYQTNGEIICKCGQAWGTMMVHKGLDLPCLKIRNFV
VNFKNNSPKKQYKKWVELPIRFPDLDYSEYCL
3D structure
PDB6g19 Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
ChainA
Resolution3.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:6g19, PDBe:6g19, PDBj:6g19
PDBsum6g19
PubMed30449722
UniProtQ8R5F7|IFIH1_MOUSE Interferon-induced helicase C domain-containing protein 1 (Gene Name=Ifih1)

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