Structure of PDB 6g0o Chain A

Receptor sequence
>6g0oA (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPT
3D structure
PDB6g0o Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W81 P82 V87 L94 P95 D96 Y139 K141 D145 I146 M149 W40 P41 V46 L53 P54 D55 Y98 K100 D104 I105 M108
External links
PDB RCSB:6g0o, PDBe:6g0o, PDBj:6g0o
PDBsum6g0o
PubMed30554943
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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