Structure of PDB 6fyr Chain A

Receptor sequence
>6fyrA (length=355) Species: 9606 (Homo sapiens) [Search protein sequence]
SSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHA
RGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFN
FHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHEN
QLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFD
HEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTH
ENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKEN
CKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTP
EERSF
3D structure
PDB6fyr X-ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan-McDermid Syndrome.
ChainA
Resolution1.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.12.1: dual-specificity kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EAQ A A184 F236 L238 L239 K241 L290 D320 A57 F109 L111 L112 K114 L163 D193
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6fyr, PDBe:6fyr, PDBj:6fyr
PDBsum6fyr
PubMed29985556
UniProtP49761|CLK3_HUMAN Dual specificity protein kinase CLK3 (Gene Name=CLK3)

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