Structure of PDB 6fxi Chain A

Receptor sequence
>6fxiA (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
MNLERLAENTGEFQEVVRAFYDTLDAARSSIRVVRVERVSHPLLQQQYEL
YRERLLQRCERRPVEQVLYHGTTAPAVPDICAHGFNRSFCGRNATVYGKG
VYFARRASLSVQDRYSPPNADGHKAVFVARVLTGDYGQGRRGLRAPPLRG
PGHVLLRYDSAVDCICQPSIFVIFHDTQALPTHLITCEHV
3D structure
PDB6fxi Human PARP10 (ARTD10), catalytic fragment in complex with 3-aminobenzamide and citrate
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3AB A H887 G888 R909 Y919 F920 A921 L926 S927 Y932 I987 H70 G71 R92 Y102 F103 A104 L109 S110 Y115 I170
Gene Ontology
Molecular Function
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity

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Molecular Function
External links
PDB RCSB:6fxi, PDBe:6fxi, PDBj:6fxi
PDBsum6fxi
PubMed
UniProtQ53GL7|PAR10_HUMAN Protein mono-ADP-ribosyltransferase PARP10 (Gene Name=PARP10)

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