Structure of PDB 6fpy Chain A

Receptor sequence
>6fpyA (length=600) Species: 9606 (Homo sapiens) [Search protein sequence]
DTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKT
AFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTME
QFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDV
DIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSC
PTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVV
FVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSL
VQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNH
ASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFL
EVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLA
LTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDE
EEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQAL
QMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDPRRTFVLSALQPSP
3D structure
PDB6fpy Heavy chain-1 of inter-alpha-inhibitor has an integrin-like structure with immune regulatory activities
ChainA
Resolution2.339 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A S300 S302 D403 G404 S256 S258 D359 G360
External links
PDB RCSB:6fpy, PDBe:6fpy, PDBj:6fpy
PDBsum6fpy
PubMed32144206
UniProtP19827|ITIH1_HUMAN Inter-alpha-trypsin inhibitor heavy chain H1 (Gene Name=ITIH1)

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