Structure of PDB 6fhq Chain A

Receptor sequence
>6fhqA (length=58) Species: 9606 (Homo sapiens) [Search protein sequence]
HMSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFC
PACIAKAS
3D structure
PDB6fhq Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C1934 C1937 H1957 C1960 C9 C12 H32 C35
BS02 ZN A C1949 C1952 C1975 C1978 C24 C27 C50 C53
BS03 DE5 A E1944 L1948 D1950 W1973 E19 L23 D25 W48 MOAD: Kd=3.4mM
PDBbind-CN: -logKd/Ki=2.47,Kd=3.4mM
External links
PDB RCSB:6fhq, PDBe:6fhq, PDBj:6fhq
PDBsum6fhq
PubMed29529862
UniProtQ9UIF8|BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B (Gene Name=BAZ2B)

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