Structure of PDB 6fhb Chain A

Receptor sequence
>6fhbA (length=302) Species: 9606 (Homo sapiens) [Search protein sequence]
ATVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTK
SSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGE
LFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDR
NVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADM
WSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKD
FIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKAAAVNMEKFKKFA
AR
3D structure
PDB6fhb Molecular mechanisms behind DAPK regulation: how phosphorylation switches work
ChainA
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D139 K141 N144 D161 T180
Catalytic site (residue number reindexed from 1) D139 K141 N144 D161 T180
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A K42 E64 K42 E64
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6fhb, PDBe:6fhb, PDBj:6fhb
PDBsum6fhb
PubMed
UniProtP53355|DAPK1_HUMAN Death-associated protein kinase 1 (Gene Name=DAPK1)

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