Structure of PDB 6fdq Chain A

Receptor sequence
>6fdqA (length=239) Species: 471472 (Chlamydia trachomatis L2/434/Bu) [Search protein sequence]
VPAWDSDIIFKCLCYFHTLYPGLIPLETFPPATIFNFKQKIISILEDKKA
VLRGEPIKGPLPICCSKENYRRHLQRTTLLPVFMWYHPTPKTLSDTMQTM
KQLAIKGSVGASHWLLVIVDIQARRLVYFDSLYNYVMPPENMKKELQSFA
QQLDQVYPAYDSKKFSVKIAAKEVIQRGSGSSCGAWCCQFLHWYLKDPLT
DALNDLPVDSVERHENLASFVQACEAAVQDLPELSWPEA
3D structure
PDB6fdq Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2UQ A W247 M262 L265 A266 S270 V271 S274 W276 C345 W85 M100 L103 A104 S108 V109 S112 W114 C183 PDBbind-CN: -logKd/Ki=3.95,IC50=113uM
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6fdq, PDBe:6fdq, PDBj:6fdq
PDBsum6fdq
PubMed30028574
UniProtB0B9A0|CDUB1_CHLT2 Deubiquitinase and deneddylase Dub1 (Gene Name=cdu1)

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