Structure of PDB 6fam Chain A

Receptor sequence
>6famA (length=350) Species: 657309 (Bacteroides xylanisolvens XB1A) [Search protein sequence]
NNLGTELDYDTFCFYYDWYGSEAIDGQYRHWAHAIAPDPNGGSGQNPGTI
PGTQESIASNFYPQLGRYSSSDPNILTKHMDMFVMARTGVLALTWWNEQD
ETEAKRIGLILDAADKKKIKVCFHLEPYPSRNVQNLRENIVKLITRYGNH
PAFYRKDGKPLFFIYDSYLIEPSEWEKLLSPGGSITIRNTAYDALMIGLW
TSSPTVQRPFILNAHFDGFYTYFAATGFTYGSTPTNWVSMQKWAKENGKI
FIPSVGPGYIDTRIRPWNGSVIRTRTDGQYYDAMYRKAIEAGVSAISITS
FNEWHEGSQIEPAVPYTSSEFTYLDYENREPDYYLTRTAYWVGKFRESKQ
3D structure
PDB6fam Exploration of Strategies for Mechanism-Based Inhibitor Design for Family GH99 endo-alpha-1,2-Mannanases.
ChainA
Resolution1.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A H63 R295 E333 H335 E336 H33 R265 E303 H305 E306 PDBbind-CN: -logKd/Ki=4.01,Kd=97.7uM
BS02 G63 A Y46 W126 H154 E156 Y195 Y252 E333 E336 Y16 W96 H124 E126 Y165 Y222 E303 E306 PDBbind-CN: -logKd/Ki=4.01,Kd=97.7uM
Gene Ontology
Molecular Function
GO:0004559 alpha-mannosidase activity
GO:0016787 hydrolase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:6fam, PDBe:6fam, PDBj:6fam
PDBsum6fam
PubMed29508463
UniProtD6D1V7

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