Structure of PDB 6fa5 Chain A

Receptor sequence
>6fa5A (length=635) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]
AQRTIQEVRKSLPVYAYRDAFLDAVKEYQVLILVGETGSGKTTQIPQYLH
EAGYTKGNRKIACTQPRRVAAMSVAARVADEMGVRLGHEVGYSIRFEDCT
SEKTILKYMTDGMLLREMVTSPDLADYSCIMIDEAHERTVHTDILLALIK
DLTRARPELRLIISSATLNAEKFSAYFDDAPIFNVPGRVHPVEVYYTSAP
ESNYLEAALVTVFQIHATQPEGDILVFLTGQEEIERACERVEEIRRKLGK
RVPEIIALPIYSNMPSEMQAKIFEPTPPGARKVVFSTNIAETSLTIDGIV
YVIDSGYVKENTFSPVGTTGQSTLAVVPCSRAAANQRMGRAGRVKPGKCF
RLYTKYAYLSEMDESPTPEIQRTSLSSVVLQLKALGIDDLLGFDFLDPPP
TELLIKSLNMLYALGALNSAGQLTRVGRQMGEFPTEPMLAKALIAATQEG
CVSEVLTIVSMLGEVGTLFFRPKDKKVHADSARARFTVRDGGDHLTLLNI
YNQWVEAEYSPIWARENFLAQRSLTRARDVRDQLAKLCDRILDGSEASCG
GVNNPTPILRALTAAFFLNAARLNRAGDGYRTLKNNITVYVHPSSVVRGM
DPPPKVIIYHELVVTSKEYVRSVIPVEPRWLSEFG
3D structure
PDB6fa5 Crystal structure of the spliceosomal DEAH-box ATPase Prp2.
ChainA
Resolution2.303 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A T322 G323 S324 G325 K326 T327 T328 R362 F558 T580 R628 T37 G38 S39 G40 K41 T42 T43 R77 F273 T295 R343 MOAD: Kd=179nM
PDBbind-CN: -logKd/Ki=6.75,Kd=179nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6fa5, PDBe:6fa5, PDBj:6fa5
PDBsum6fa5
PubMed29968674
UniProtG0SEG4

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