Structure of PDB 6f7l Chain A

Receptor sequence
>6f7lA (length=431) Species: 1928 (Streptomyces rochei) [Search protein sequence]
VVEAKSRIAVVGGGGSGSVAAWLLARRHDVTLFEADEYLGGHAYSHPVET
DQGTLHVDMGVEHFNEKLSPNLFRLLTDFGIGTYVAPSSVHVDFPGEQQS
WNNLDFLGELREELHEEFDRFHQEMNQLPTSKQMSIGEYLDKHGYSKSFK
YKAMNPILSIYSGCHAPSLDYNLMYVALSFSMNLLSFFSAGYWRKAQGGI
HSYLARIESDLGERVRLNTPVEAVVPTQSGVTVLAGGQEHHFDQVVFATH
ADVTLRLLRTSDQQYRDLLGDFAYVPVESVLHQDESWLSPAGGGAYCQFR
MPEGFELARAEEQMGSLTQNCNVLHPYRKVSSPILITFDPQEDVDPERVI
VRREWKLPQLRPVDVRRKKRLHEIQGLNGLWFCGTDTSVTGHEGAIVSGM
VIADRLGVPHPFPDDAPAAAQFRGIKEFMGV
3D structure
PDB6f7l Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FAD A G14 G16 S18 E36 A37 G43 H44 G62 V63 E64 H65 V228 T256 H257 L364 G391 T392 G398 H399 G12 G14 S16 E34 A35 G41 H42 G60 V61 E62 H63 V221 T249 H250 L357 G384 T385 G391 H392
BS02 CWH A E64 I167 Y168 Y182 Q326 V396 T397 E62 I160 Y161 Y175 Q319 V389 T390
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6f7l, PDBe:6f7l, PDBj:6f7l
PDBsum6f7l
PubMed30266997
UniProtQ83X90

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