Structure of PDB 6f6n Chain A

Receptor sequence
>6f6nA (length=253) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
SIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPS
ATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRG
FPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVV
AFLILPQAGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFL
LQLNETIYTSGKRSNTTGKLIWKVNPEIDTTWAFWETSEELSFTVVAAAA
AAA
3D structure
PDB6f6n Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SRE A R64 V66 A101 R33 V35 A70 MOAD: Kd=0.95mM
PDBbind-CN: -logKd/Ki=3.02,Kd=0.95mM
BindingDB: Kd=950000nM
External links
PDB RCSB:6f6n, PDBe:6f6n, PDBj:6f6n
PDBsum6f6n
PubMed29272110
UniProtQ05320|VGP_EBOZM Envelope glycoprotein (Gene Name=GP)

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