Structure of PDB 6f4n Chain A

Receptor sequence
>6f4nA (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
LIPDVKLEKTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSL
EYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYL
AQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQD
PQQNFLVQVMGRKYIRLYSPQESGALYPHDTHHNTSQVDVENPDLEKFPK
FAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS
3D structure
PDB6f4n JMJD5 is a human arginyl C-3 hydroxylase.
ChainA
Resolution2.541 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.73: [protein]-arginine 3-hydroxylase.
3.4.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H321 D323 H400 H148 D150 H225
BS02 AKG A Y272 W310 S318 H321 N327 H400 V402 W414 Y99 W137 S145 H148 N154 H225 V227 W239 PDBbind-CN: -logKd/Ki=5.22,IC50=6uM
External links
PDB RCSB:6f4n, PDBe:6f4n, PDBj:6f4n
PDBsum6f4n
PubMed29563586
UniProtQ8N371|KDM8_HUMAN Bifunctional peptidase and arginyl-hydroxylase JMJD5 (Gene Name=KDM8)

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