Structure of PDB 6f34 Chain A

Receptor sequence
>6f34A (length=458) Species: 235909 (Geobacillus kaustophilus HTA426) [Search protein sequence]
MNLFRKKPIQLLMKESGAKGASLRKELGAFDLTMLGIGAIIGTGIFVLTG
VAAAEHAGPALVLSFILSGLACVFAALCYAEFASTVPVSGSAYTYSYATF
GELIAWILGWDLILEYGVASSAVAVGWSGYFQGLLSGELPKALTSAYDPA
KGTFIDLPAIIIVLFITFLLNLGAKKSARFNAVIVAIKVAVVLLFLAVGV
WYVKPENWTPFMPYGFSGVATGAATVFFAYIGFDAVSTAAEEVRNPQRDM
PIGIIVSLLVCTLLYIAVSLVLTGIVPYEQLNVKNPVAFALNYIHQDWVA
GFISLGAIAGITTVLLVSMYGQTRLFYAISRDGLLPKVFARISPTRQVPY
VNTWLTGAAVAVFAGIIPLNKLAELTNIGTLFAFITVSIGVLVLRKTQPD
LKRAFRVPFVPVVPILAVLFCGYLVLQLPAMTWIGFVSWLLIGLVIYFIY
GRKHSELN
3D structure
PDB6f34 Structural basis for amino acid transport by the CAT family of SLC7 transporters.
ChainA
Resolution3.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G28 F30 D31 M34 A181 R182 A189 I190 A193 L197 Q299 V302 G28 F30 D31 M34 A178 R179 A186 I187 A190 L194 Q296 V299
BS02 ARG A I40 G42 T43 G44 E115 Y116 A119 F231 A232 I234 V317 I40 G42 T43 G44 E115 Y116 A119 F228 A229 I231 V314 PDBbind-CN: -logKd/Ki=4.94,IC50=11.4uM
BS03 CLR A W204 Y205 W201 Y202
Gene Ontology
Molecular Function
GO:0015171 amino acid transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006865 amino acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6f34, PDBe:6f34, PDBj:6f34
PDBsum6f34
PubMed29416041
UniProtQ5L1G5

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