Structure of PDB 6f1h Chain A

Receptor sequence
>6f1hA (length=291) Species: 9606 (Homo sapiens) [Search protein sequence]
SIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEP
SEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFH
TDFSNEENGTIMFYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHN
YVGGYFCSCRPGYELQEDTHSCQAECSSELYTEASGYISSLEYPRSYPPD
LRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEF
CGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIK
3D structure
PDB6f1h Structure of the C1r-C1s interaction of the C1 complex of complement activation.
ChainA
Resolution4.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.41: complement subcomponent C1r.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E49 D57 T101 D102 S104 N105 E49 D57 T101 D102 S104 N105
BS02 CA A D125 L126 E128 N150 Y151 G154 D125 L126 E128 N150 Y151 G154
BS03 CA A Y197 D226 D236 D273 S275 Y197 D226 D236 D273 S275
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:6f1h, PDBe:6f1h, PDBj:6f1h
PDBsum6f1h
PubMed29311313
UniProtP00736|C1R_HUMAN Complement C1r subcomponent (Gene Name=C1R)

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