Structure of PDB 6ey7 Chain A

Receptor sequence
>6ey7A (length=225) Species: 10360 (Human herpesvirus 5 strain AD169) [Search protein sequence]
LITDQSREEFDILRYSTLNTNAYDYFGKTLYVYLDPAFTRKASGTGVAAV
GAYRHQFLIYGLEHFFLRDLSESSEVAIAECAAHMIISVLSLHPYLDELR
IAVEGNTNQAAAVRIACLIRQSVQSSTLIRVLFYHTPDQNHIEQPFYLMG
RDKALAVEQFISRFNSGYIKASQELVSYTIKLSHDPIEYLLEQIQNLHRS
DDLIIAVIMATYLCDDIHAIRFRVS
3D structure
PDB6ey7 Structure-Driven Discovery of alpha , gamma-Diketoacid Inhibitors Against UL89 Herpesvirus Terminase.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D463 E534 D35 E104
BS02 MN A D463 D651 D35 D202
BS03 C3W A F466 S473 N536 M579 G580 F38 S43 N106 M149 G150 PDBbind-CN: -logKd/Ki=4.30,IC50=50uM
Gene Ontology
Biological Process
GO:0051276 chromosome organization

View graph for
Biological Process
External links
PDB RCSB:6ey7, PDBe:6ey7, PDBj:6ey7
PDBsum6ey7
PubMed31458978
UniProtP16732|TRM3_HCMVA Tripartite terminase subunit 3 (Gene Name=TRM3)

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